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Losing weight with vibra­tion pill

The topic of weight loss is the subject of count­less discus­sions — in the general media as well as among experts. Never is there a time when diffe­rent diets are not compared with each other, and curr­ently the so-called “weight loss injec­tion” (Ozempic® and Wegovy®) is causing a furore. But even here there are reports of side effects and long-term studies are still pending.

It is hardly surpri­sing that a tech­nical rather than a phar­ma­co­lo­gical approach is temp­ting. Espe­ci­ally when no such drastic inter­ven­tion as stomach reduc­tion or intestinal shor­tening is necessary.

Rese­ar­chers at the Massa­chu­setts Insti­tute of Tech­no­logy (MIT) and Harvard Univer­sity have now deve­loped a small vibra­ting device that is swal­lowed, then adheres to the stomach lining, where it stimu­lates the stomach wall for around half an hour and is finally excreted via the gastro­in­testinal tract. The mecha­n­o­re­cep­tors of the stomach conclude that the stomach is full as a result of the stimu­la­tion, and the body reacts accor­dingly with a change in eating beha­viour. The rese­ar­chers demons­trated this in animal expe­ri­ments on young pigs. There were no unde­si­rable effects.

Our conclu­sion: All in all, an exci­ting idea, even if it is still a long way off…


You can find the original study here:

Srini­vasan, Shriya S et al. A vibra­ting inges­tible bioelec­tronic stimu­lator modu­lates gastric stretch recep­tors for illu­sory satiety. Science advances vol. 9,51 (2023). DOI: 10.1126/sciadv.adj3003