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Weight loss, fact-checked: the not-so-small difference

Geschlechts­un­ter­schiede beim Ab…

Same diet.

Same trai­ning volume.

Diffe­rent results:

He loses four kilos. She loses her pati­ence. But what are the reasons for this “gender weight gap”?

Muscle mass: The starting point is not identical

On average, men have around 10–15% more fat-free mass than women of the same age. The share of skeletal muscle is about 40–45% of body weight in men, and more like 30–35% in women. More muscle mass, however, also means a higher basal meta­bolic rate: One kilo­gram of fat-free mass burns about 13–15 kcal per day at rest.

  • In prac­tice, this often results in a daily energy expen­diture that is about 100–300 kcal higher for men.

Energy regu­la­tion: Earlier counter-regulation

In women, hormonal regu­la­tion reacts more sensi­tively to energy defi­cits. The level of the satiety hormone leptin can drop by 30–50% even with mode­rate rest­ric­tion, while the hunger hormone ghrelin increases. At the same time, adap­tive ther­mo­ge­nesis reduces energy expen­diture by 5–15%.

  • A woman’s body ther­e­fore dampens expen­diture earlier and more consistently.

Cycle: Weight is not a fixed refe­rence value

Weight fluc­tua­tions of 1–2 kg within a cycle are physio­lo­gical. In the luteal phase, basal meta­bolic rate increases by 2–10%, while at the same time, in many women spon­ta­neous energy intake increases by 90–500 kcal per day. Proges­te­rone addi­tio­nally promotes fluid retention.

  • Short-term scale values ther­e­fore often show the hormonal dyna­mics — not actual fat change.

Meno­pause: When distri­bu­tion changes

With meno­pause, visceral fat volume increases by around 40–60%, while muscle mass decreases signi­fi­cantly — even if total body weight increases only moderately.

  • On the one hand, visceral fat is meta­bo­li­cally active and promotes insulin resis­tance, inflamm­a­tory processes and cardio­vas­cular risk. On the other hand, with less muscle mass, resting energy expen­diture can be around 100–200 kcal per day lower.

So what is espe­ci­ally important for women

  • Strength trai­ning + suffi­cient protein: 2–3×/week progres­sive trai­ning; 1.6–2.0 g protein/kg BW, to secure muscle mass and basal meta­bolic rate
  • Mode­rate calorie deficit: about 300–500 kcal instead of crash diet
  • Plan for cycle & life stage: 1–2 kg cyclical fluc­tua­tions are physio­lo­gical; post­me­no­pausal, focus more on waist circum­fe­rence, strength values and meta­bolic markers)

What do you think: Do weight-loss stra­te­gies suffi­ci­ently take sex diffe­rences into account?

Szeliga A et al. The Impact of the Meno­pausal Tran­si­tion on Body Compo­si­tion and Abdo­minal Fat Redis­tri­bu­tion. J Clin Med. 2026 Jan 16;15(2):740.