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Natu­rally effec­tive? Cran­ber­ries for urinary tract infections

Cran­berry juice is a classic remedy for urinary tract infections—and is one of the home reme­dies that has been rela­tively well studied. However, the key point is often over­looked: cran­ber­ries are prima­rily effec­tive as a preven­tive measure.

Preven­tion rather than treatment

Studies show that the effect is parti­cu­larly evident in women with recur­rent urinary tract infec­tions. The number of new infec­tions can decrease with regular consump­tion. Accor­ding to a Coch­rane review, the risk of recur­rent infec­tions is reduced by about 25–30% in women; the effect appears to be slightly stronger in children. Some groups, such as pregnant women and nursing home resi­dents, did not benefit.
In cases of acute bladder infec­tions, there is hardly any posi­tive effect. Once the infec­tion has taken hold, the mecha­nism simply comes too late—the bacteria have already atta­ched them­selves to the mucous membrane and are multiplying.

What’s Behind the Effect

Accor­ding to studies, simply drin­king more water alone can signi­fi­cantly reduce the number of recur­rent urinary tract infec­tions. However, the effect of cran­ber­ries is not about “flus­hing,” but rather the active compounds contained in the plant: proan­tho­cya­ni­dins (PACs), which make it diffi­cult for bacteria to attach to the bladder lining. E. coli, the most common cause of urinary tract infec­tions, relies on this adhe­sion. Without it, it becomes signi­fi­cantly harder for the bacteria to estab­lish them­selves in the urinary tract.

Juice, capsules, or extract—and how much, exactly?

And how and in what quan­tity is it best to take cran­berry? There is no stan­dard dosage recom­men­da­tion. Studies often use about 36 mg of proan­tho­cya­ni­dins per day. It is not possible to give a general figure for how much juice is needed, as the proan­tho­cya­nidin content varies signi­fi­cantly depen­ding on the product. When taking dietary supple­ments, you should pay atten­tion to the infor­ma­tion regar­ding PAC content.

Williams G et al. Cran­ber­ries for preven­ting urinary tract infec­tions. Coch­rane Data­base Syst Rev. 2023;4(4):CD001321.